A fast 512-element ring array photoacoustic imaging system for small animals

John Gamelin; Anastasios Maurudis; Andres Aguirre; Fei Huang; Puyun Guo; Lihong V. Wang; Quing Zhu

doi:10.1117/12.812406

24 February 2009 A fast 512-element ring array photoacoustic imaging system for small animals

John Gamelin, Anastasios Maurudis, Andres Aguirre, Fei Huang, Puyun Guo, Lihong V. Wang, Quing Zhu

Proceedings Volume 7177, Photons Plus Ultrasound: Imaging and Sensing 2009; 71770B (2009) https://doi.org/10.1117/12.812406
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed. The system features a 5 MHz piezocomposite transducer array formed into a complete circular aperture. Custom receiver electronics consisting of dedicated preamplifiers, 8:1 multiplexed post-amplifiers, and a 64-channel data acquisition module provide full tomographic imaging at up to 8 frames/second. We present details of the system design along with characterization results of the resolution, imaging volume, and sensitivity. Small animal imaging performance is demonstrated through images of mice brain vasculature at different depths and real-time spectroscopic scans. This system enables real-time tomographic imaging for functional photoacoustic studies for the first time.

Citation Download Citation

John Gamelin, Anastasios Maurudis, Andres Aguirre, Fei Huang, Puyun Guo, Lihong V. Wang, and Quing Zhu "A fast 512-element ring array photoacoustic imaging system for small animals", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71770B (24 February 2009); https://doi.org/10.1117/12.812406

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