PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
Rod shaped gold nanoparticles are synthesized using cetyltriammonium bromide (CTAB) as a major component of
growth solutions. This surfactant is toxic to cells, but is at the moment unavoidable when monodisperse and high yield
nanorods are to be synthesized. CTAB is found coating side walls of the nanoparticles and plays a role in maintaining
colloidal stability. It may be displaced using thiolated PEG which is non-toxic to cells. Here we report on systematic
studies of cell viability of such PEGylated nanorods on an SKBR3 cell-line using the MTS assay. These PEGylated
particles are characterized using electron microscopy, optical spectroscopy and zeta potential measurements. It is
expected that such treatment will be crucial in making nanorods compatible for in vivo biomedical applications.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Srirang Manohar, Rajagopal Rayavarapu, Wilma Petersen, Ton G. van Leeuwen, "Cell viability studies of PEG-thiol treated gold nanorods as optoacoustic contrast agents," Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 71772D (24 February 2009); https://doi.org/10.1117/12.808547