Optical microcavities: single virus detection and nanoparticle trapping

Frank Vollmer; Stephen Arnold

doi:10.1117/12.827264

21 August 2009 Optical microcavities: single virus detection and nanoparticle trapping

Frank Vollmer, Stephen Arnold

Proceedings Volume 7397, Biosensing II; 739702 (2009) https://doi.org/10.1117/12.827264
Event: SPIE NanoScience + Engineering, 2009, San Diego, California, United States

Abstract

Single polystyrene nanoparticles are detected from resonance wavelength fluctuations in toroidal and spherical microcavities. The magnitude of the wavelength-shift signal follows a reactive mechanism with inverse dependence on mode volume. By reducing the size of a microsphere cavity we demonstrate sensitivity to single Influenza A virions. Furthermore, we introduce a novel mechanism for trapping and accumulation of nanoparticles at the microcavity-sensorregion by utilizing light-force exerted in evanescent field gradients.

Citation Download Citation

Frank Vollmer and Stephen Arnold "Optical microcavities: single virus detection and nanoparticle trapping", Proc. SPIE 7397, Biosensing II, 739702 (21 August 2009); https://doi.org/10.1117/12.827264

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