New multimodal multiphoton imaging and spectroscopy apparatus for dermatology

Yingqiu Yu; Anthony Lee; Hequn Wang; Jianhua Zhao; Shuo Tang; Harvey Lui; David I. McLean; Haishan Zeng

doi:10.1117/12.847112

23 March 2010 New multimodal multiphoton imaging and spectroscopy apparatus for dermatology

Yingqiu Yu, Anthony Lee, Hequn Wang, Jianhua Zhao, Shuo Tang, Harvey Lui, David I. McLean, Haishan Zeng

Proceedings Volume 7548, Photonic Therapeutics and Diagnostics VI; 75480N (2010) https://doi.org/10.1117/12.847112
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

We present the construction of a new multimodal, multiphoton spectroscopic and imaging instrument for in vivo patient use. Utilizing a tunable femtosecond laser, we are able to simultaneously acquire two-photon excited fluorescence, second harmonic generation, and confocal reflectance images at half video rate, while concurrently acquiring two-photon excited fluorescence and second harmonic generation spectra.

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Yingqiu Yu, Anthony Lee, Hequn Wang, Jianhua Zhao, Shuo Tang, Harvey Lui, David I. McLean, and Haishan Zeng "New multimodal multiphoton imaging and spectroscopy apparatus for dermatology", Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 75480N (23 March 2010); https://doi.org/10.1117/12.847112

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KEYWORDS

Imaging spectroscopy

Confocal microscopy

Skin cancer

Luminescence

Second-harmonic generation

Spectroscopes

Dermatology

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