Fluorescent protein imaging with multispectral optoacoustic tomography

Daniel Razansky; Martin Distel; Claudio Vinegoni; Rui Ma; Reinhard Köster; Vasilis Ntziachristos

doi:10.1117/12.842775

23 February 2010 Fluorescent protein imaging with multispectral optoacoustic tomography

Daniel Razansky, Martin Distel, Claudio Vinegoni, Rui Ma, Reinhard Köster, Vasilis Ntziachristos

Proceedings Volume 7564, Photons Plus Ultrasound: Imaging and Sensing 2010; 75641R (2010) https://doi.org/10.1117/12.842775
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

In this work, we have developed a selective-plane illumination multispectral optoacoustic tomography (MSOT) technique for high-resolution whole-body visualization of intact optically diffusive organisms whose sizes may vary from sub-millimeter up to a centimeter range and beyond. By combining multi-wavelength illumination, the method is shown capable of resolving tissue-specific expression of fluorescent proteins and other molecular biomarkers located deep in living optically diffuse tissues.

Citation Download Citation

Daniel Razansky, Martin Distel, Claudio Vinegoni, Rui Ma, Reinhard Köster, and Vasilis Ntziachristos "Fluorescent protein imaging with multispectral optoacoustic tomography", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75641R (23 February 2010); https://doi.org/10.1117/12.842775

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