Spatial resolution of ultrasound-modulated optical tomography used for the detection of absorbing and scattering objects in thick scattering media

Guy Rousseau; Alain Blouin; Jean-Pierre Monchalin

doi:10.1117/12.841828

23 February 2010 Spatial resolution of ultrasound-modulated optical tomography used for the detection of absorbing and scattering objects in thick scattering media

Guy Rousseau, Alain Blouin, Jean-Pierre Monchalin

Author Affiliations +

Proceedings Volume 7564, Photons Plus Ultrasound: Imaging and Sensing 2010; 75642A (2010) https://doi.org/10.1117/12.841828
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Ultrasound-modulated optical tomography (UOT) combines the spatial resolution of ultrasonic waves and the spectroscopic properties of light to detect optically absorbing and/or scattering objects in highly scattering media. In this work, a double-pass confocal Fabry-Perot interferometer is used as a bandpass filter to selectively detect the ultrasoundtagged photons. The limited etendue of the confocal Fabry-Perot interferometer is compensated by using a singlefrequency laser emitting high-peak-power optical pulses. Compared to photoacoustic tomography, UOT is not only sensitive to optical absorption but also to scattering properties. In this paper, we consider the detection of absorbing and scattering objects embedded in thick (30 to 60 mm) tissue-mimicking phantoms and biological tissues. The experimental evaluation of the spatial resolution of the technique is compared to that expected from the ultrasonic beam intensity profile. Preliminary results indicate that the edge spread function is influenced by the level of absorption of the embedded object.

Citation Download Citation

Guy Rousseau, Alain Blouin, and Jean-Pierre Monchalin "Spatial resolution of ultrasound-modulated optical tomography used for the detection of absorbing and scattering objects in thick scattering media", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75642A (23 February 2010); https://doi.org/10.1117/12.841828

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