Photoacoustic tomography of foreign bodies in soft biological tissue

Xin Cai; Chulhong Kim; Manojit Pramanik; Lihong V. Wang

doi:10.1117/12.845942

23 February 2010 Photoacoustic tomography of foreign bodies in soft biological tissue

Xin Cai, Chulhong Kim, Manojit Pramanik, Lihong V. Wang

Proceedings Volume 7564, Photons Plus Ultrasound: Imaging and Sensing 2010; 75643H (2010) https://doi.org/10.1117/12.845942
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Ultrasound imaging suffers from poor sensitivity (~50%) and specificity in detecting small foreign bodies in tissue. Hence, alternative imaging methods are needed. Photoacoustic (PA) imaging takes advantage of strong optical absorption contrast and high ultrasonic resolution. This work employed a PA imaging system to detect foreign bodies in biological tissues. To achieve deep penetration, we used near-infrared light and a 5-MHz spherically focused ultrasonic transducer. PA images were obtained from objects (glass, wood, cloth, plastic, and metal) embedded in chicken tissue. The location and size of the targets from the PA images agreed well with those of the actual samples. Objects were imaged more than 1 cm deep. Spectroscopic PA imaging was also performed on the objects. These results suggest PA imaging can potentially be a useful intraoperative imaging tool to identify foreign bodies and discriminate viable tissues in wounded patients.

Citation Download Citation

Xin Cai, Chulhong Kim, Manojit Pramanik, and Lihong V. Wang "Photoacoustic tomography of foreign bodies in soft biological tissue", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75643H (23 February 2010); https://doi.org/10.1117/12.845942

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