A portable instrument for the optical interrogation of a novel biochip

F. Baldini; L. Bolzoni; A. Giannetti; G. Porro; C. Trono

doi:10.1117/12.866456

8 September 2010 A portable instrument for the optical interrogation of a novel biochip

F. Baldini, L. Bolzoni, A. Giannetti, G. Porro, C. Trono

Proceedings Volume 7653, Fourth European Workshop on Optical Fibre Sensors; 76531H (2010) https://doi.org/10.1117/12.866456
Event: (EWOFS'10) Fourth European Workshop on Optical Fibre Sensors, 2010, Porto, Portugal

Abstract

In the present paper a novel optical system for the monitoring and measurements of different analytes in Point of Care Testing (POCT) is presented. It is based on an optical biochip constituted by a two-piece polymethylmetacrylate (PMMA) chip, with 13 microchannels through which the analysed sample flows, and the sensing layer, where the immunochemical reaction takes place, is located on the bottom side of the upper piece of the PMMA chip. All the electronics, optoelectronics and fluidics components are embedded in a portable instrument is totally controlled by software. Preliminary tests on C-reactive protein (CRP) and procalcitonin (PCT) immunoassay are reported.

Citation Download Citation

F. Baldini, L. Bolzoni, A. Giannetti, G. Porro, and C. Trono "A portable instrument for the optical interrogation of a novel biochip", Proc. SPIE 7653, Fourth European Workshop on Optical Fibre Sensors, 76531H (8 September 2010); https://doi.org/10.1117/12.866456

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