Optimization of an impedance sensor for droplet-based microfluidic systems

Brian P. Cahill

doi:10.1117/12.886887

5 May 2011 Optimization of an impedance sensor for droplet-based microfluidic systems

Brian P. Cahill

Proceedings Volume 8066, Smart Sensors, Actuators, and MEMS V; 80660F (2011) https://doi.org/10.1117/12.886887
Event: SPIE Microtechnologies, 2011, Prague, Czech Republic

Abstract

Digital microfluidics utilises discrete droplets to increase the throughput of chemical and biological assays. There is a great need for sensing techniques that can help automate droplet handing. This work aims to illustrate by means of finite element modelling the factors that affect the measurement of droplet impedance in a thin-walled glass capillary. These include modelling the effect of varying capillary wall thickness, electrode spacing, electrode area, droplet size, shielding and droplet conductivity. The simulation is performed using COMSOL finite element analysis software. The model serves to aid the optimization of the measurement system for application in the measurement of the presence/absence of droplets as well as their chemical and biological content.

Citation Download Citation

Brian P. Cahill "Optimization of an impedance sensor for droplet-based microfluidic systems", Proc. SPIE 8066, Smart Sensors, Actuators, and MEMS V, 80660F (5 May 2011); https://doi.org/10.1117/12.886887

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available