High frequency intravascular photoacoustic (IVPA) imaging for differentiating arterial wall layered structures

Xiang Li; Wei Wei; Qifa Zhou; K. Kirk Shung; Zhongping Chen

doi:10.1117/12.906581

9 February 2012 High frequency intravascular photoacoustic (IVPA) imaging for differentiating arterial wall layered structures

Xiang Li, Wei Wei, Qifa Zhou, K. Kirk Shung, Zhongping Chen

Author Affiliations +

Proceedings Volume 8207, Photonic Therapeutics and Diagnostics VIII; 820746 (2012) https://doi.org/10.1117/12.906581
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Arterial wall is composed of three layers: intima, media and adventitia. Intima-media thickness (IMT) is an important prognostic indicator of atherosclerotic diseases. Although intravascular ultrasound (IVUS) imaging is a commonly used method for delineation of the layered structures, it is inferior to the optical absorption contrast offered by intravascular photoacoustic (IVPA) imaging. We introduce an integrated miniature probe that combines the capabilities of IVUS and IVPA imaging for the evaluation of arterial wall layered structures. Healthy rabbit aorta was imaged ex vivo. IVPA results showed superior contrast over IVUS in identifying the layered structures of arterial wall.

Citation Download Citation

Xiang Li, Wei Wei, Qifa Zhou, K. Kirk Shung, and Zhongping Chen "High frequency intravascular photoacoustic (IVPA) imaging for differentiating arterial wall layered structures", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 820746 (9 February 2012); https://doi.org/10.1117/12.906581

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