In vivo human retinal and choroidal vasculature visualization using differential phase contrast swept source optical coherence tomography at 1060 nm

Reza Motaghiannezam; Scott Fraser

doi:10.1117/12.910991

30 January 2012 In vivo human retinal and choroidal vasculature visualization using differential phase contrast swept source optical coherence tomography at 1060 nm

Reza Motaghiannezam, Scott Fraser

Author Affiliations +

Proceedings Volume 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI; 821304 (2012) https://doi.org/10.1117/12.910991
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

A differential phase contrast (DPC) method is validated for in vivo human retinal and choroidal vasculature visualization using high-speed swept-source optical coherence tomography (SS-OCT) at 1060 nm. The vasculature was identified as regions of motion by creating differential phase variance (DPV) tomograms: multiple B-scans were collected of individual slices through the retina and the variance of the phase differences was calculated. DPV captured the small vessels and the meshwork of capillaries associated with the inner retina in en face images over 4 mm² in a normal subject. En face DPV images were capable of capturing the microvasculature and regions of motion through the inner retina and choroid.

Citation Download Citation

Reza Motaghiannezam and Scott Fraser "In vivo human retinal and choroidal vasculature visualization using differential phase contrast swept source optical coherence tomography at 1060 nm", Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 821304 (30 January 2012); https://doi.org/10.1117/12.910991

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