Compact clinical high-NA multiphoton endoscopy

Martin Weinigel; Hans Georg Breunig; Peter Fischer; Marcel Kellner-Höfer; Rainer Bückle; Karsten König

doi:10.1117/12.908755

2 March 2012 Compact clinical high-NA multiphoton endoscopy

Martin Weinigel, Hans Georg Breunig, Peter Fischer, Marcel Kellner-Höfer, Rainer Bückle, Karsten König

Proceedings Volume 8217, Endoscopic Microscopy VII; 821706 (2012) https://doi.org/10.1117/12.908755
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Multiphoton imaging methods are excellent for non-invasive imaging of living tissue without any need of additional contrast agents. The increasing demand for endoscopic techniques has forced the development of multiphoton endoscopes for imaging of areas with reduced accessibility like chronic wounds. Gradient index (GRIN) lenses can miniaturize the bulky distal focusing optics of conventional tomographs to a diameter of less than 1.4 mm and a numerical aperture (NA) of 0.8. We combined a high NA clinical multiphoton endoscope with existing multiphoton tomographs like the DermaInspect® and the MPTflex® to enable the examination of wound healing processes.

Citation Download Citation

Martin Weinigel, Hans Georg Breunig, Peter Fischer, Marcel Kellner-Höfer, Rainer Bückle, and Karsten König "Compact clinical high-NA multiphoton endoscopy", Proc. SPIE 8217, Endoscopic Microscopy VII, 821706 (2 March 2012); https://doi.org/10.1117/12.908755

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