Spectral grading and Gleason grading of malignant prostate tissue using Stokes shift spectra

M. Al Salhi; V. Masilamani; D. Rabah; K. Farhat; C. H. Liu; Y. Pu; R. R. Alfano

doi:10.1117/12.906906

8 February 2012 Spectral grading and Gleason grading of malignant prostate tissue using Stokes shift spectra

M. Al Salhi, V. Masilamani, D. Rabah, K. Farhat, C. H. Liu, Y. Pu, R. R. Alfano

Proceedings Volume 8220, Optical Biopsy X; 82200J (2012) https://doi.org/10.1117/12.906906
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Gleason score is the most common method of grading the virulence of prostate malignancy and is based on the pathological assessment of morphology of cellular matrix. Since this involves the excision of the tissue, we are working on a new, minimally invasive, non contact, procedure of spectral diagnosis of prostate malignancy. In this preliminary in vitro study reported here, we have analyzed 27 tissue samples (normal control =7: benign=8: malignant =12) by Stokes' shift spectra (SSS) to establish a one- to- one correlation between spectral grading and Gleason grading.

Citation Download Citation

M. Al Salhi, V. Masilamani, D. Rabah, K. Farhat, C. H. Liu, Y. Pu, and R. R. Alfano "Spectral grading and Gleason grading of malignant prostate tissue using Stokes shift spectra", Proc. SPIE 8220, Optical Biopsy X, 82200J (8 February 2012); https://doi.org/10.1117/12.906906

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