VIS-NIR spectrum analysis for distinguishing tumor and normal human breast tissue

Yang Zhang; Yuan Yu; Valery V. Tuchin; Yongjun Chen; Xiang Wen; Caihua Liu; Jing Wang; Xingbo Xue; Dan Zhu

doi:10.1117/12.914760

9 February 2012 VIS-NIR spectrum analysis for distinguishing tumor and normal human breast tissue

Yang Zhang, Yuan Yu, Valery V. Tuchin, Yongjun Chen, Xiang Wen, Caihua Liu, Jing Wang, Xingbo Xue, Dan Zhu

Proceedings Volume 8222, Dynamics and Fluctuations in Biomedical Photonics IX; 82221C (2012) https://doi.org/10.1117/12.914760
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

The high incidence and mortality of breast cancer require an effective method for early breast diagnosis. In order to investigate the optical differences among malignant tumor, benign tumor and normal human breast tissue, a commercial spectrophotometer combined with single integrating sphere was used to measure the optical properties of different types of breast tissue in the wavelength range of 400 nm to 2200 nm in vitro. The hematoxylin and eosin staining (H&E staining) are used as the standard, and to find the find possible optical markers from the corresponding absorption or scattering spectra. This work is not only used for in vitro rapid optical diagnosis, but very helpful to develop innovative optical diagnosis of breast tumor in vivo.

Citation Download Citation

Yang Zhang, Yuan Yu, Valery V. Tuchin, Yongjun Chen, Xiang Wen, Caihua Liu, Jing Wang, Xingbo Xue, and Dan Zhu "VIS-NIR spectrum analysis for distinguishing tumor and normal human breast tissue", Proc. SPIE 8222, Dynamics and Fluctuations in Biomedical Photonics IX, 82221C (9 February 2012); https://doi.org/10.1117/12.914760

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