In-plane spatial resolution measurements of a phase-contrast tomosynthesis prototype

Di Wu; Hui Miao; Yuhua Li; Xizeng Wu; Hong Liu

doi:10.1117/12.910126

14 February 2012 In-plane spatial resolution measurements of a phase-contrast tomosynthesis prototype

Di Wu, Hui Miao, Yuhua Li, Xizeng Wu, Hong Liu

Proceedings Volume 8224, Biophotonics and Immune Responses VII; 82240D (2012) https://doi.org/10.1117/12.910126
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

The objectives of this project are to intrinsically and quantitatively investigate the advantages of a phase-contrast (PC) tomosynthesis prototype in removing the superimposed structure noise and the effects on image qualities by an off-center shift of the object along the tube-sweep direction. Experimentally, phantoms are assembled with standard resolution patterns. Phase-contrast tomosynthesis images are acquired and reconstructed. In order to study the effects of the limited angular projections on the in-plane resolutions, all the images were reconstructed in the 2×2 binning mode only, as we will study the phase contrast effects elsewhere. The in-plane slices reconstructed from each of the experiments examined and the in-plane limiting resolutions are determined. For comparison, the resolution patterns and phantoms are also imaged by single projections. Under single x-ray projection, with only one resolution pattern, the limiting resolution of the system is 8 lp/mm; with 2 resolution patterns superimposed, the image of the resolution patterns is blurred for distinguishing line pairs. The PC tomosynthesis in-plane images show that the limiting resolution of the system is 7 lp/mm. For objects with a shift along the horizontal axis (the tube-sweep direction) by 0.8 inch, the spatial resolution is degraded to 4 lp/mm and blur occurs. As is expected, the PC tomosynthesis prototype studied in this project reveals superimposed fine structures of the object; the effect induced by the object's off-center shift is determined in a quantified way. The in-plane resolution of this system can be further improved by optimizing the system alignment, and the reconstruction algorithms.

Citation Download Citation

Di Wu, Hui Miao, Yuhua Li, Xizeng Wu, and Hong Liu "In-plane spatial resolution measurements of a phase-contrast tomosynthesis prototype", Proc. SPIE 8224, Biophotonics and Immune Responses VII, 82240D (14 February 2012); https://doi.org/10.1117/12.910126

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