Influence of air bubbles on the recovery of optical properties

Jose Alberto Delgado Atencio; Beatriz Morales Cruzado; Sergio Vázquez y Montiel

doi:10.1117/12.909325

2 February 2012 Influence of air bubbles on the recovery of optical properties

Jose Alberto Delgado Atencio, Beatriz Morales Cruzado, Sergio Vázquez y Montiel

Proceedings Volume 8229, Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV; 82291K (2012) https://doi.org/10.1117/12.909325
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

In some vital organs of the human body the air bubbles are indicative of the presence of disease. On the other hand, poor information has been published considering the effect of air bubbles on the optical properties of tissue mimicking phantoms. The goal of this study was to investigate the influence of air bubbles on the optical properties of polyurethane phantoms. A two-integrating spheres system (TISS) in combination with the IAD method was used to determine the optical properties of a set of polyurethane phantoms fabricated with different levels of air bubbles. Phantoms were characterized with a microscope and a fiber optic spectrometer using a two-fiber probe. Results indicate that the TISS in conjunction with the IAD method is insensitive to the level of air bubbles within polyurethane phantoms whereas that for the spectrometric system a noticeable difference was found for the spectra of phantoms prepared with different levels of air bubbles. A change of reflectance spectra above 25 % at 428 nm was found when degassing sample time changed from 5 to 10 minutes. This finding indicates that controlling the degassing step of phantoms is more critical when they are required for the validation and standardization of devices that have a robust working principle based on the probing of a localized volume such as it is the case of fiber optic probes.

Citation Download Citation

Jose Alberto Delgado Atencio, Beatriz Morales Cruzado, and Sergio Vázquez y Montiel "Influence of air bubbles on the recovery of optical properties", Proc. SPIE 8229, Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV, 82291K (2 February 2012); https://doi.org/10.1117/12.909325

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available