Paper
2 February 2012 Lasing modes in disordered media for single-nanoparticle quantitation: a new approach for biosensing
Seung Ho Choi, Young L. Kim
Author Affiliations +
Abstract
Since random lasers were the objective of fundamental investigation, they have awaited utilities in biomedical applications. We investigate the feasibility that random lasing modes in disordered media can be used for singlenanoparticle quantitation. Our numerical experiments reveal that minute alterations in a single nanoparticle can induce dramatic changes in the eigenmodes of the system, which are self-formed in the disordered media, and that the multiple modes can serve as a "fine fishnet" to capture any perturbations. Combining its simplicity of realization and its sensitivity, random lasers could potentially serve a new biosensing mechanism.
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Seung Ho Choi and Young L. Kim "Lasing modes in disordered media for single-nanoparticle quantitation: a new approach for biosensing", Proc. SPIE 8230, Biomedical Applications of Light Scattering VI, 823008 (2 February 2012); https://doi.org/10.1117/12.905911
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KEYWORDS
Random lasers

Nanoparticles

Biosensing

Particles

Biomedical optics

Scattering

Digital signal processing

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