Towards diffuse optical tomography of arbitrarily heterogeneous turbid medium using GPU-accelerated Monte-Carlo forward calculation

Xi Yi; Weiting Chen; Linhui Wu; Wei Zhang; Jiao Li; Xin Wang; Limin Zhang; Huijuan Zhao; Feng Gao

doi:10.1117/12.2001970

13 March 2013 Towards diffuse optical tomography of arbitrarily heterogeneous turbid medium using GPU-accelerated Monte-Carlo forward calculation

Xi Yi, Weiting Chen, Linhui Wu, Wei Zhang, Jiao Li, Xin Wang, Limin Zhang, Huijuan Zhao, Feng Gao

Author Affiliations +

Proceedings Volume 8574, Multimodal Biomedical Imaging VIII; 85740O (2013) https://doi.org/10.1117/12.2001970
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

At present, the most widely accepted forward model in diffuse optical tomography (DOT) is the diffusion equation, which is derived from the radiative transfer equation by employing the P1 approximation. However, due to its validity restricted to highly scattering regions, this model has several limitations for the whole-body imaging of small-animals, where some cavity and low scattering areas exist. To overcome the difficulty, we presented a Graphic-Processing- Unit(GPU) implementation of Monte-Carlo (MC) modeling for photon migration in arbitrarily heterogeneous turbid medium, and, based on this GPU-accelerated MC forward calculation, developed a fast, universal DOT image reconstruction algorithm. We experimentally validated the proposed method using a continuous-wave DOT system in the photon-counting mode and a cylindrical phantom with a cavity inclusion.

Citation Download Citation

Xi Yi, Weiting Chen, Linhui Wu, Wei Zhang, Jiao Li, Xin Wang, Limin Zhang, Huijuan Zhao, and Feng Gao "Towards diffuse optical tomography of arbitrarily heterogeneous turbid medium using GPU-accelerated Monte-Carlo forward calculation", Proc. SPIE 8574, Multimodal Biomedical Imaging VIII, 85740O (13 March 2013); https://doi.org/10.1117/12.2001970

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