Cardiovascular CTA applications: patient-specific contrast formulae

C. Saade; R. Bourne; M. Wilkinson; P. Brennan

doi:10.1117/12.2007697

28 March 2013 Cardiovascular CTA applications: patient-specific contrast formulae

C. Saade, R. Bourne, M. Wilkinson, P. Brennan

Proceedings Volume 8673, Medical Imaging 2013: Image Perception, Observer Performance, and Technology Assessment; 86731R (2013) https://doi.org/10.1117/12.2007697
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Clear visualisation of the vertebral arteries is of substantial clinical importance, yet optimisation of contrast administration has not been developed in tandem with recent technological developments in computed tomography (CT). The current work involving 202 patients’ compares the value of a tailored contrast regiment based on patient dynamics and a craniocaudal scan acquisition, with the routine contrast protocol with a caudocranial scan. Attenuation characteristics within 20 arteries were calculated and diagnostic efficacy measured using DBM receiver operating characteristic (ROC) methods. The results demonstrated that the tailored regimen resulted in significantly higher attenuation values (p<0.01) and ROC Az values (p=0.002), along with better inter-observer agreement compared with the routine protocol and contrast volume was reduced by almost 50%. The data demonstrate that patient-specific strategies can result in significant diagnostic benefit.

Citation Download Citation

C. Saade, R. Bourne, M. Wilkinson, and P. Brennan "Cardiovascular CTA applications: patient-specific contrast formulae", Proc. SPIE 8673, Medical Imaging 2013: Image Perception, Observer Performance, and Technology Assessment, 86731R (28 March 2013); https://doi.org/10.1117/12.2007697

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