Modeling of a single red blood cell thermal reaction exposed to infrared laser tweezers

A. Seteikin; I. Krasnikov; I. Bernhardt

doi:10.1117/12.2016846

26 February 2013 Modeling of a single red blood cell thermal reaction exposed to infrared laser tweezers

A. Seteikin, I. Krasnikov, I. Bernhardt

Proceedings Volume 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV; 86990P (2013) https://doi.org/10.1117/12.2016846
Event: Saratov Fall Meeting and Workshop on Laser Physics and Photonics 2012, 2012, Saratov, Russian Federation

Abstract

Continuous-wave laser micro-beams are generally used as diagnostic tools in laser scanning microscopes or in the case of near-infrared (NIR) micro-beams, as optical traps for cell manipulation and force characterization. Because single beam traps are created with objectives of high numerical aperture, typical trapping intensities and photon flux densities are in the order of 10⁶ W/cm² and 10³ cm^-2s^-1, respectively. The main idea of our theoretical study was to investigate the thermal reaction of RBCs irradiated by laser micro-beam. The study is supported by the fact that many experiments have been carried out with RBCs in laser NIR tweezers. In the present work it has been identified that the laser affects a RBC with a density of absorbed energy at approximately 10⁷ J/cm³, which causes a temperature rise in the cell of about 7 – 12 °C.

Citation Download Citation

A. Seteikin, I. Krasnikov, and I. Bernhardt "Modeling of a single red blood cell thermal reaction exposed to infrared laser tweezers", Proc. SPIE 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV, 86990P (26 February 2013); https://doi.org/10.1117/12.2016846

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KEYWORDS

Optical tweezers

Absorption

Near infrared

Blood

Objectives

Water

Continuous wave operation

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