A diffuse reflectance spectroscopy system to study biological tissues

A. de la Cadena; S. Stolik; J. M. de la Rosa

doi:10.1117/12.2026477

18 November 2013 A diffuse reflectance spectroscopy system to study biological tissues

A. de la Cadena, S. Stolik, J. M. de la Rosa

Proceedings Volume 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications; 8785E8 (2013) https://doi.org/10.1117/12.2026477
Event: 8th Ibero American Optics Meeting/11th Latin American Meeting on Optics, Lasers, and Applications, 2013, Porto, Portugal

Abstract

Diffuse reflectance spectroscopy (DRS) is a technique that allows the study of the structural and biochemical condition of tissues in a noninvasive-nonionizing way. DRS has been widely used in biomedical applications, mainly as an alternative to biopsy. Generally, the technique consists in the irradiation of a specific zone of a tissue with a reference spectrum. Then, the reemitted by the tissue light is detected. The changes suffered by the backscattered spectrum (after light-tissue interaction) with respect to the incident one carry information about the tissue properties. This work presents a novel system designed and developed to use DRS in biomedical applications. The system uses a LED as a light source and a specially designed optical fiber probe as a mean to deliver the light to the tissue surface, and to collect the reemitted photons from the studied sample. This probe was designed to accomplish two different tasks: to increase the sensitivity of the diagnosis; and to study the radial dependence of the backscattered light. The measuring probe was built in a way that allows taking readings when the exerted pressure on the tissue reaches certain predetermined values.

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A. de la Cadena, S. Stolik, and J. M. de la Rosa "A diffuse reflectance spectroscopy system to study biological tissues", Proc. SPIE 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications, 8785E8 (18 November 2013); https://doi.org/10.1117/12.2026477

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KEYWORDS

Tissues

Diffuse reflectance spectroscopy

Optical fibers

Tissue optics

Light sources

Optical design

Photons

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