High speed 3D endoscopic optical frequency domain imaging probe for lung cancer diagnosis

Jianan Li; Fabio Feroldi; Jianhua Mo; Frank Helderman; Mattijs de Groot; Johannes F. de Boer

doi:10.1117/12.2032569

18 June 2013 High speed 3D endoscopic optical frequency domain imaging probe for lung cancer diagnosis

Jianan Li, Fabio Feroldi, Jianhua Mo, Frank Helderman, Mattijs de Groot, Johannes F. de Boer

Author Affiliations +

Proceedings Volume 8802, Optical Coherence Tomography and Coherence Techniques VI; 88020E (2013) https://doi.org/10.1117/12.2032569
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

We present a miniature motorized endoscopic probe for Optical Frequency Domain Imaging with an outer diameter of 1.65 mm and a rotation speed of 3,000 – 12,500 rpm. The probe has a motorized distal end which provides a significant advantage over proximally driven probes since it does not require a drive shaft to transfer the rotational torque to the distal end of the probe and functions without a fiber rotary junction. The probe has a focal Full Width at Half Maximum of 9.6 μm and a working distance of 0.47 mm. We analyzed the non-uniform rotation distortion and found a location fluctuation of only 1.87° in repeated measurements of the same object. The probe was integrated in a high-speed Optical Frequency Domain Imaging setup at 1310 nm. We demonstrated its performance with imaging ex vivo pig bronchial and in vivo goat lung.

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Jianan Li, Fabio Feroldi, Jianhua Mo, Frank Helderman, Mattijs de Groot, and Johannes F. de Boer "High speed 3D endoscopic optical frequency domain imaging probe for lung cancer diagnosis", Proc. SPIE 8802, Optical Coherence Tomography and Coherence Techniques VI, 88020E (18 June 2013); https://doi.org/10.1117/12.2032569

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KEYWORDS

Endoscopy

Optical imaging

In vivo imaging

Optical coherence tomography

Distortion

Lung

Gradient-index optics

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