A model for ultrasound modulated light in a turbid medium

Joseph L. Hollmann; Roarke Horstmeyer; Changhuei Yang; Charles A. DiMarzio

doi:10.1117/12.2041179

12 March 2014 A model for ultrasound modulated light in a turbid medium

Joseph L. Hollmann, Roarke Horstmeyer, Changhuei Yang, Charles A. DiMarzio

Proceedings Volume 8949, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXI; 89490U (2014) https://doi.org/10.1117/12.2041179
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

The ability to focus light in most tissue degrades quickly with depth due to high optical scattering. Researchers have investigated using both ultrasound (US) and light synergistically to overcome this difficulty. Ultrasound has been utilized to modulated light within tissue to create a diffusive wave at that is modulated at the US frequency. Recently, there has been interest in the modulated sidebands which reside at optical frequency plus or minus the US frequency. This paper will discuss a model for US-light interactions in a scattering medium. We will use this model to relate the radiance in the probe beam to the radiance in the diffusive wave. We will then employ the P-1 approximation to the radiative transport equation to find the fluence and flux of the modulated wave. We will use these parameters to write a diffusion equation for the modulated wave that can be described in terms of the incoming optical power, and the US intensity and geometry.

Citation Download Citation

Joseph L. Hollmann, Roarke Horstmeyer, Changhuei Yang, and Charles A. DiMarzio "A model for ultrasound modulated light in a turbid medium", Proc. SPIE 8949, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXI, 89490U (12 March 2014); https://doi.org/10.1117/12.2041179

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available