Quenching of the luminescence of nanomarkers bound to proteins by heavy metals

Julia Konyukhova; Andrei Melnikov; Gennadiy Melnikov; Ekaterina Naumova; Alexander Skaptsov; Elena Volkova; Vyacheslav Kochubey

doi:10.1117/12.2051829

30 January 2014 Quenching of the luminescence of nanomarkers bound to proteins by heavy metals

Julia Konyukhova, Andrei Melnikov, Gennadiy Melnikov, Ekaterina Naumova, Alexander Skaptsov, Elena Volkova, Vyacheslav Kochubey

Author Affiliations +

Proceedings Volume 9031, Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV; 90310K (2014) https://doi.org/10.1117/12.2051829
Event: Saratov Fall Meeting 2013, 2013, Saratov, Russian Federation

Abstract

The effect of heavy metal ions on the fluorescence of semiconductor ZnCdS nanoparticles in albumin solution was studied. It was found that the fluorescence intensity of ZnCdS nanoparticles depends on the albumin concentration in the solution. Interacting with ZnCdS nanoparticles, heavy metals differently affect the fluorescence intensity of the nanoparticles. Copper ions induce fluorescence quenching, cadmium ions increases the fluorescence intensity, and zinc ions do not affect the fluorescence intensity. ZnCdS nanoparticles are most sensitive to copper ions. Albumin enhances the effect of copper ions. The results on the influence of heavy metals on the fluorescence intensity of ZnCdS nanoparticles can be used to create a selective sensor for determination of copper ions in proteins using fluorescence quenching.

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Julia Konyukhova, Andrei Melnikov, Gennadiy Melnikov, Ekaterina Naumova, Alexander Skaptsov, Elena Volkova, and Vyacheslav Kochubey "Quenching of the luminescence of nanomarkers bound to proteins by heavy metals", Proc. SPIE 9031, Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV, 90310K (30 January 2014); https://doi.org/10.1117/12.2051829

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