Phase contrast portal imaging for image-guided microbeam radiation therapy

Keiji Umetani; Takeshi Kondoh

doi:10.1117/12.2043216

19 March 2014 Phase contrast portal imaging for image-guided microbeam radiation therapy

Keiji Umetani, Takeshi Kondoh

Proceedings Volume 9033, Medical Imaging 2014: Physics of Medical Imaging; 90335P (2014) https://doi.org/10.1117/12.2043216
Event: SPIE Medical Imaging, 2014, San Diego, California, United States

Abstract

High-dose synchrotron microbeam radiation therapy is a unique treatment technique used to destroy tumors without severely affecting circumjacent healthy tissue. We applied a phase contrast technique to portal imaging in preclinical microbeam radiation therapy experiments. Phase contrast portal imaging is expected to enable us to obtain higherresolution X-ray images at therapeutic X-ray energies compared to conventional portal imaging. Frontal view images of a mouse head sample were acquired in propagation-based phase contrast imaging. The phase contrast images depicted edge-enhanced fine structures of the parietal bones surrounding the cerebrum. The phase contrast technique is expected to be effective in bony-landmark-based verification for image-guided radiation therapy.

Citation Download Citation

Keiji Umetani and Takeshi Kondoh "Phase contrast portal imaging for image-guided microbeam radiation therapy", Proc. SPIE 9033, Medical Imaging 2014: Physics of Medical Imaging, 90335P (19 March 2014); https://doi.org/10.1117/12.2043216

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available