Mapping cardiac fiber orientations from high-resolution DTI to high-frequency 3D ultrasound

Xulei Qin; Silun Wang; Ming Shen; Xiaodong Zhang; Mary B. Wagner; Baowei Fei

doi:10.1117/12.2043821

12 March 2014 Mapping cardiac fiber orientations from high-resolution DTI to high-frequency 3D ultrasound

Xulei Qin, Silun Wang, Ming Shen, Xiaodong Zhang, Mary B. Wagner, Baowei Fei

Proceedings Volume 9036, Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling; 90361O (2014) https://doi.org/10.1117/12.2043821
Event: SPIE Medical Imaging, 2014, San Diego, California, United States

Abstract

The orientation of cardiac fibers affects the anatomical, mechanical, and electrophysiological properties of the heart. Although echocardiography is the most common imaging modality in clinical cardiac examination, it can only provide the cardiac geometry or motion information without cardiac fiber orientations. If the patient’s cardiac fiber orientations can be mapped to his/her echocardiography images in clinical examinations, it may provide quantitative measures for diagnosis, personalized modeling, and image-guided cardiac therapies. Therefore, this project addresses the feasibility of mapping personalized cardiac fiber orientations to three-dimensional (3D) ultrasound image volumes. First, the geometry of the heart extracted from the MRI is translated to 3D ultrasound by rigid and deformable registration. Deformation fields between both geometries from MRI and ultrasound are obtained after registration. Three different deformable registration methods were utilized for the MRI-ultrasound registration. Finally, the cardiac fiber orientations imaged by DTI are mapped to ultrasound volumes based on the extracted deformation fields. Moreover, this study also demonstrated the ability to simulate electricity activations during the cardiac resynchronization therapy (CRT) process. The proposed method has been validated in two rat hearts and three canine hearts. After MRI/ultrasound image registration, the Dice similarity scores were more than 90% and the corresponding target errors were less than 0.25 mm. This proposed approach can provide cardiac fiber orientations to ultrasound images and can have a variety of potential applications in cardiac imaging.

Citation Download Citation

Xulei Qin, Silun Wang, Ming Shen, Xiaodong Zhang, Mary B. Wagner, and Baowei Fei "Mapping cardiac fiber orientations from high-resolution DTI to high-frequency 3D ultrasound", Proc. SPIE 9036, Medical Imaging 2014: Image-Guided Procedures, Robotic Interventions, and Modeling, 90361O (12 March 2014); https://doi.org/10.1117/12.2043821

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