DMD-based spatially Fourier-encoded photoacoustic microscopy

Jinyang Liang; Liang Gao; Chiye Li; Lihong V. Wang

doi:10.1117/12.2076783

11 March 2015 DMD-based spatially Fourier-encoded photoacoustic microscopy

Jinyang Liang, Liang Gao, Chiye Li, Lihong V. Wang

Proceedings Volume 9323, Photons Plus Ultrasound: Imaging and Sensing 2015; 932324 (2015) https://doi.org/10.1117/12.2076783
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

We present spatially Fourier-encoded photoacoustic microscopy using a digital micromirror device (DMD). The spatial fluence distribution of laser pulses is Fourier-encoded by the DMD, and a series of such encoded photoacoustic (PA) measurements enables decoding of the spatial distribution of optical absorption. By imaging a chromium target, we demonstrated the throughput and Fellgett advantages, which increased the PA signal-to-noise ratio (SNR) compared to raster scanning. The system was used to image two biological targets, a monolayer of red blood cells, and melanoma cells. The enhanced SNR benefited PA images by increasing the image’s contrast-to-noise ratio and target identifiability.

Citation Download Citation

Jinyang Liang, Liang Gao, Chiye Li, and Lihong V. Wang "DMD-based spatially Fourier-encoded photoacoustic microscopy", Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932324 (11 March 2015); https://doi.org/10.1117/12.2076783

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KEYWORDS

Signal to noise ratio

Raster graphics

Digital micromirror devices

Computer programming

Absorption

Image enhancement

Photoacoustic microscopy

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