Gold-nanoshells as surface plasmon resonance (SPR)

K. Sathiyamoorthy; Michael C. Kolios

doi:10.1117/12.2080303

9 March 2015 Gold-nanoshells as surface plasmon resonance (SPR)

Proceedings Volume 9332, Optical Diagnostics and Sensing XV: Toward Point-of-Care Diagnostics; 93320G (2015) https://doi.org/10.1117/12.2080303
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Coreshell plasmonic nanoparticles (CS) are a class of nanoparticles that exhibit optical absorption in the near IR regime and have potential biomedical applications in imaging, therapy and sensing. We present our preliminary investigation on the applications of CS as a surface plasmon based sensor to study the functional properties of human blood. CS particles of size about 1 μm exhibit broad absorption between 650 nm to 1000 nm, the regime generally used to study blood saturation. We synthesized CS particles of size about 1μm, coated with a thin shell. The core medium was polystyrene and the nano-shell layer was gold. The plasmon peak of CS varied with blood concentration. The study showed that 750 nm plasmonic peak of CS exhibits the wavelength shift of 4.11±0.26 nm per hematocrit.

Citation Download Citation

K. Sathiyamoorthy and Michael C. Kolios "Gold-nanoshells as surface plasmon resonance (SPR)", Proc. SPIE 9332, Optical Diagnostics and Sensing XV: Toward Point-of-Care Diagnostics, 93320G (9 March 2015); https://doi.org/10.1117/12.2080303

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