Review of dermatology use of 5-aminolevulinic acid photodynamic therapy in China from 1997 to 2013

Peiru Wang; Guolong Zhang; Xiuli Wang

doi:10.1117/12.2183290

15 July 2015 Review of dermatology use of 5-aminolevulinic acid photodynamic therapy in China from 1997 to 2013

Peiru Wang, Guolong Zhang, Xiuli Wang

Author Affiliations +

Proceedings Volume 9542, Medical Laser Applications and Laser-Tissue Interactions VII; 954206 (2015) https://doi.org/10.1117/12.2183290
Event: European Conferences on Biomedical Optics, 2015, Munich, Germany

Abstract

The prodrug 5-aminolevulinic acid (ALA) and its ester derivatives have been used in photodynamic therapy (PDT) in dermatology worldwide. In China, ALA-PDT was first used to treat urethral condylomata acuminata and non-melanoma skin cancers in 1997. A powder formulation of ALA hydrochloride was approved by the Chinese Food and Drug Administration for the treatment of condylomata acuminata in 2007. Large successful experience of treating condylomatas was accumulated compared with Western countries. Meanwhile, numerous clinical studies as well as off-label use of ALAPDT have been carried out in China. To reflect the progress of ALA-PDT in China, several major Chinese and English databases were searched and published data were reviewed in this article.

Citation Download Citation

Peiru Wang, Guolong Zhang, and Xiuli Wang "Review of dermatology use of 5-aminolevulinic acid photodynamic therapy in China from 1997 to 2013", Proc. SPIE 9542, Medical Laser Applications and Laser-Tissue Interactions VII, 954206 (15 July 2015); https://doi.org/10.1117/12.2183290

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