Imunohistological aspects of the tissue around dental implants

Victor Nimigean; Vanda Roxana Nimigean; Dan Ionut Sălăvăstru; Simona Moraru; Lavinia Buţincu; Roxana Victoria Ivaşcu; Alexandru Poll

doi:10.1117/12.2197741

22 March 2016 Imunohistological aspects of the tissue around dental implants

Victor Nimigean, Vanda Roxana Nimigean, Dan Ionut Sălăvăstru, Simona Moraru, Lavinia Buţincu, Roxana Victoria Ivaşcu, Alexandru Poll

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Proceedings Volume 9670, Sixth International Conference on Lasers in Medicine; 96700O (2016) https://doi.org/10.1117/12.2197741
Event: Sixth International Conference on Lasers in Medicine, 2015, Bucharest, Romania

Abstract

Objectives: study of soft and hard tissues around implants. Material and methods: For the immunohistochemical and histological study of the implant/soft tissue interface, we examined pieces of peri-implant mucosa harvested from 35 patients. The implant/bone interface was assessed using histologic and histomorphometric examination of hard tissues around unloaded, early loaded or delayed loaded dental implants with pre-established design, with a sandblasted and acid-etched surface, placed both in extraction sockets, or after bone healing following tooth removal. This study was performed on 9 common race dogs. Results: The histological study of the implant/soft tissue interface showed regenerative modifications and moderate chronic subepithelial inflammatory reactions. Immunohistochemical evaluation of the soft tissue biopsies revealed the presence of specific immunocompetent cells and proteins of the matrix metalloproteinase (MMP) expression. Bone-implants contacts were more obvious in the apical half of the implants and at the edges of the threads, than between them. A mature, lamelliform bone containing lacunae with osteocytes and lack of connective tissue were noticed around implants that were late placed and loaded. The new-formed bone was also abundant in the crestal zone, not only in the apical part of the implants. Conclusions: A thorough understanding of the microstructure of dental implant/soft and hard tissue interface will improve the longevity of osseointegrated implants.

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Victor Nimigean, Vanda Roxana Nimigean, Dan Ionut Sălăvăstru, Simona Moraru, Lavinia Buţincu, Roxana Victoria Ivaşcu, and Alexandru Poll "Imunohistological aspects of the tissue around dental implants", Proc. SPIE 9670, Sixth International Conference on Lasers in Medicine, 96700O (22 March 2016); https://doi.org/10.1117/12.2197741

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KEYWORDS

Tissues

Bone

Interfaces

Connective tissue

Medicine

Natural surfaces

Proteins

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