Optimization of modified scanning protocol based correlation mapping optical coherence tomography at 200 kHz VCSEL source for in vivo microcirculation imaging applications

Cerine Lal; James McGrath; Hrebesh Subhash; Martin Leahy

doi:10.1117/12.2214797

21 March 2016 Optimization of modified scanning protocol based correlation mapping optical coherence tomography at 200 kHz VCSEL source for in vivo microcirculation imaging applications

Cerine Lal, James McGrath, Hrebesh Subhash, Martin Leahy

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Proceedings Volume 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX; 96973C (2016) https://doi.org/10.1117/12.2214797
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Optical Coherence Tomography (OCT) is a non-invasive 3 dimensional optical imaging modality that enables high resolution cross sectional imaging in biological tissues and materials. Unlike other 3 D medical imaging modalities, OCT provides high axial and lateral resolution combined with high sensitivity, imaging depth and wide field of view which makes it suitable for wide variety of medical imaging applications1. Apart from analysing the morphological characteristics of the biological organs with micron scale axial and lateral resolution, OCT also provides functional information from the biological sample. Among the various functional extensions of OCT, angiographic OCT that enables visualization of lumens of blood vessels from the acquired OCT B scan images has been of high research interest in the recent past.

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Cerine Lal, James McGrath, Hrebesh Subhash, and Martin Leahy "Optimization of modified scanning protocol based correlation mapping optical coherence tomography at 200 kHz VCSEL source for in vivo microcirculation imaging applications", Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96973C (21 March 2016); https://doi.org/10.1117/12.2214797

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KEYWORDS

Optical coherence tomography

Angiography

Capillaries

Microcirculation imaging

Vertical cavity surface emitting lasers

In vivo imaging

Image resolution

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