Spatially resolved diffuse reflectance spectroscopy of two-layer turbid media by densely packed multi-pixel photodiode reflectance probe

Ozlem Senlik; Gage Greening; Timothy J. Muldoon; Nan M. Jokerst

doi:10.1117/12.2213124

18 March 2016 Spatially resolved diffuse reflectance spectroscopy of two-layer turbid media by densely packed multi-pixel photodiode reflectance probe

Ozlem Senlik, Gage Greening, Timothy J. Muldoon, Nan M. Jokerst

Author Affiliations +

Proceedings Volume 9700, Design and Quality for Biomedical Technologies IX; 97000O (2016) https://doi.org/10.1117/12.2213124
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Spatially–resolved diffuse reflectance (SRDR) measurements provide photon path information, and enable layered tissue analysis. This paper presents experimental SRDR measurements on two-layer PDMS skin tissue-mimicking phantoms of varying top layer thicknesses, and bulk phantoms of varying optical properties using concentric multi-pixel photodiode array (CMPA) probes, and corresponding forward Monte Carlo simulations. The CMPA is the most densely packed semiconductor SRDR probe reported to date. Signal contrasts between the single layer phantom and bi-layer phantoms with varying top layer thicknesses are as high as 80%. The mean error between the Monte Carlo simulations and the experiment is less than 6.2 %.

Citation Download Citation

Ozlem Senlik, Gage Greening, Timothy J. Muldoon, and Nan M. Jokerst "Spatially resolved diffuse reflectance spectroscopy of two-layer turbid media by densely packed multi-pixel photodiode reflectance probe", Proc. SPIE 9700, Design and Quality for Biomedical Technologies IX, 97000O (18 March 2016); https://doi.org/10.1117/12.2213124

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available