Investigation on laser-assisted tissue repair with NIR millisecond-long light pulses and Indocyanine Green-biopolymeric patches

Paolo Matteini; Martina Banchelli; Maximilien Cottat; Iacopo Osticioli; Marella de Angelis; Francesca Rossi; Roberto Pini

doi:10.1117/12.2214621

7 March 2016 Investigation on laser-assisted tissue repair with NIR millisecond-long light pulses and Indocyanine Green-biopolymeric patches

Paolo Matteini, Martina Banchelli, Maximilien Cottat, Iacopo Osticioli, Marella de Angelis, Francesca Rossi, Roberto Pini

Author Affiliations +

Proceedings Volume 9702, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI; 97020A (2016) https://doi.org/10.1117/12.2214621
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

In previous works a minimally invasive laser-assisted technique for vascular repair was presented. The technique rests on the photothermal adhesion of a biocompatible and bioresorbable patch containing Indocyanine Green that is brought into contact with the site to be repaired. Afterward the use of NIR millisecond-long light pulses generates a strong welding effect between the patch and the underlying tissue and in turn the repair of the wound. This technique was shown to be effective in animal model and provides several advantages over conventional suturing methods. Here we investigate and discuss the optical stability of the ICG-biopolymeric patches and the photothermal effects induced to the irradiated tissue.

Conference Presentation

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Paolo Matteini, Martina Banchelli, Maximilien Cottat, Iacopo Osticioli, Marella de Angelis, Francesca Rossi, and Roberto Pini "Investigation on laser-assisted tissue repair with NIR millisecond-long light pulses and Indocyanine Green-biopolymeric patches", Proc. SPIE 9702, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI, 97020A (7 March 2016); https://doi.org/10.1117/12.2214621

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