Bessel beam Grueneisen photoacoustic microscopy with extended depth of field

Junhui Shi; Lidai Wang; Cedric Noordam; Lihong V. Wang

doi:10.1117/12.2211198

15 March 2016 Bessel beam Grueneisen photoacoustic microscopy with extended depth of field

Junhui Shi, Lidai Wang, Cedric Noordam, Lihong V. Wang

Proceedings Volume 9708, Photons Plus Ultrasound: Imaging and Sensing 2016; 97083H (2016) https://doi.org/10.1117/12.2211198
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

The short focal depth of a Gaussian beam limits the volumetric imaging speed of optical resolution photoacoustic microscopy (OR-PAM). A Bessel beam, which is diffraction-free, provides a long focal depth, but its side-lobes may deteriorate image quality when the Bessel beam is directly employed to excite photoacoustic signals in ORPAM. Here, we present a nonlinear approach based on the Grueneisen relaxation effect to suppress the side-lobe artifacts in photoacoustic imaging. This method extends the focal depth of OR-PAM and speeds up volumetric imaging. We experimentally demonstrated a 1-mm focal depth with a 7-μm lateral resolution and volumetrically imaged a carbon fiber and red blood cell samples.

Citation Download Citation

Junhui Shi, Lidai Wang, Cedric Noordam, and Lihong V. Wang "Bessel beam Grueneisen photoacoustic microscopy with extended depth of field", Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97083H (15 March 2016); https://doi.org/10.1117/12.2211198

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