Optoelectronic investigation of nanodiamond interactions with human blood

M. Ficek; M. S. Wróbel; M. Wasowicz; M. Jedrzejewska-Szczerska

doi:10.1117/12.2208443

22 April 2016 Optoelectronic investigation of nanodiamond interactions with human blood

M. Ficek, M. S. Wróbel, M. Wasowicz, M. Jedrzejewska-Szczerska

Proceedings Volume 9721, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII; 97210H (2016) https://doi.org/10.1117/12.2208443
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

We present optoelectronic investigation of in vitro interactions of whole human blood with different nanodiamond biomarkers. Plasmo-chemical modifications of detonation nanodiamond particles gives the possibility for controlling their surface for biological applications. Optical investigations reveal the biological activity of nanodiamonds in blood dependent on its surface termination. We compare different types of nanodiamonds: commercial non-modified detonation nanodiamonds, and nanodiamonds modified by MW PACVD method with H₂-termination, and chemically modified nanodiamond with O₂-termination. The absorption spectra, and optical microscope investigations were conducted. The results indicate haemocompatibility of non-modified detonation nanodiamond as well as modified nanodiamonds, which enables their application for drug delivery, as well as sensing applications.

Citation Download Citation

M. Ficek, M. S. Wróbel, M. Wasowicz, and M. Jedrzejewska-Szczerska "Optoelectronic investigation of nanodiamond interactions with human blood", Proc. SPIE 9721, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII, 97210H (22 April 2016); https://doi.org/10.1117/12.2208443

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Blood

Neodymium

Optoelectronics

Microwave radiation

Oxygen

Absorption

Biomedical optics

Show All Keywords

Keywords/Phrases

Search In:

Publication Years