Comparison of membrane-protective activity of antioxidants quercetine and Gratiola Officinalis L. extract under conditions of photodynamic haemolysis

N. V. Tkachenko; E. V. Bykova; A. B. Pravdin; N. A. Navolokin; N. V. Polukonova; A. B. Bucharskaya; D. A. Mudrak; A. Y. Prilepskii

doi:10.1117/12.2228291

21 April 2016 Comparison of membrane-protective activity of antioxidants quercetine and Gratiola Officinalis L. extract under conditions of photodynamic haemolysis

N. V. Tkachenko, E. V. Bykova, A. B. Pravdin, N. A. Navolokin, N. V. Polukonova, A. B. Bucharskaya, D. A. Mudrak, A. Y. Prilepskii

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Proceedings Volume 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS); 99170L (2016) https://doi.org/10.1117/12.2228291
Event: Saratov Fall Meeting 2015, 2015, Saratov, Russian Federation

Abstract

In the present work the effectiveness of antioxidants quercetine (a pure chemical) and Gratiola officinalis extract, which is obtained by a new method of extraction from plant material, is investigated on the model of photodynamic haemolysis that is a rather convenient method to monitor the rate of cell membranes oxidative destruction. The effect of these antioxidants on the rate of photodynamic haemolysis is considered as a measure of membranoprotective efficiency.

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N. V. Tkachenko, E. V. Bykova, A. B. Pravdin, N. A. Navolokin, N. V. Polukonova, A. B. Bucharskaya, D. A. Mudrak, and A. Y. Prilepskii "Comparison of membrane-protective activity of antioxidants quercetine and Gratiola Officinalis L. extract under conditions of photodynamic haemolysis", Proc. SPIE 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 99170L (21 April 2016); https://doi.org/10.1117/12.2228291

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