Label-free parathyroid gland identification during pediatric neck surgeries with near infrared autofluorescence detection

Giju Thomas; Parker A. Willmon; Ryan Belcher; Monica Lopez; Harold N. Lovvorn III; Naira Baregamian; Carmen C. Solórzano; Anita Mahadevan-Jansen

doi:10.1117/12.2610564

7 March 2022 Label-free parathyroid gland identification during pediatric neck surgeries with near infrared autofluorescence detection

Giju Thomas, Parker A. Willmon, Ryan Belcher, Monica Lopez, Harold N. Lovvorn III, Naira Baregamian, Carmen C. Solórzano, Anita Mahadevan-Jansen

Author Affiliations +

Proceedings Volume PC11935, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2022; PC1193503 (2022) https://doi.org/10.1117/12.2610564
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Several studies have already demonstrated that near infrared autofluorescence (NIRAF) detection can be reliably used to detect parathyroid glands (PGs) in adults. However, its scope remains unexplored in the pediatric population, who are more prone to accidental PG damage during neck surgeries. Our preliminary findings obtained from pediatric patients who underwent thyroidectomies, indicate a PG detection rate of 94.4% using NIRAF detection with a fiber-optic probe-based approach. Due to the complexities associated with surgeries performed through tiny neck incisions in the pediatric population, the fiber-optic probe-based NIRAF detection can be valuable for real-time label-free PG identification during pediatric neck surgeries.

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Citation Download Citation

Giju Thomas, Parker A. Willmon, Ryan Belcher, Monica Lopez, Harold N. Lovvorn III, Naira Baregamian, Carmen C. Solórzano, and Anita Mahadevan-Jansen "Label-free parathyroid gland identification during pediatric neck surgeries with near infrared autofluorescence detection", Proc. SPIE PC11935, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2022, PC1193503 (7 March 2022); https://doi.org/10.1117/12.2610564

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