Intravascular polarization-sensitive optical coherence tomography

Yan Li; Sucbei Moon; Yuchen Jiang; Zhongping Chen

doi:10.1117/12.2607333

7 March 2022 Intravascular polarization-sensitive optical coherence tomography

Yan Li, Sucbei Moon, Yuchen Jiang, Zhongping Chen

Proceedings Volume PC11936, Diagnostic and Therapeutic Applications of Light in Cardiology 2022; PC1193603 (2022) https://doi.org/10.1117/12.2607333
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Intravascular polarization-sensitive optical coherence tomography (IV-PSOCT) provides depth-resolved tissue birefringence which can be used to evaluate the mechanical stability of a plaque. Here, we demonstrate a very simple method of constructing an intravascular polarization-sensitive optical coherence tomography (IV-PSOCT) system. A conventional intravascular OCT system can be modified for IV-PSOCT by applying a 12-m polarization-maintaining fiber based imaging probe. Its two polarization modes separately produce OCT images of polarization detection channels spatially distinguished by an image separation of 2.7 mm. We experimentally validated our IV-PSOCT with chicken tendon, chicken breast, and coronary artery for the image samples. We found that the birefringent properties can be successfully visualized by our endoscopic imaging tool.

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Citation Download Citation

Yan Li, Sucbei Moon, Yuchen Jiang, and Zhongping Chen "Intravascular polarization-sensitive optical coherence tomography", Proc. SPIE PC11936, Diagnostic and Therapeutic Applications of Light in Cardiology 2022, PC1193603 (7 March 2022); https://doi.org/10.1117/12.2607333

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KEYWORDS

Optical coherence tomography

Birefringence

Polarization

Arteries

Imaging systems

Tissue optics

Biomedical optics

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