OCT image guidance for gastrointestinal endoscopic cryobiopsy

Radhika K. Poduval; David O. Otuya; Shoumik Lodh; Seth Judson; Darina Postupaka; Abigail L. Gregg; Guillermo J. Tearney

doi:10.1117/12.2612714

7 March 2022 OCT image guidance for gastrointestinal endoscopic cryobiopsy

Radhika K. Poduval, David O. Otuya, Shoumik Lodh, Seth Judson, Darina Postupaka, Abigail L. Gregg, Guillermo J. Tearney

Proceedings Volume PC11937, Endoscopic Microscopy XVII; PC119370I (2022) https://doi.org/10.1117/12.2612714
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Endoscopic biopsies play a vital role in the diagnosis of many diseases of the gastrointestinal (GI) tract. The standard means of biopsy capture using forceps presents challenges in obtaining adequate tissue samples, especially for unsedated transnasal endoscopy (uTNE). Cryobiopsy is an emerging minimally-invasive alternative where the distal tip of a dual-lumen uTNE probe is cooled momentarily, freezing and adhering the tissue in contact, which is collected for histology. OCT image guidance during cryobiopsy can enable pre-biopsy lesion examination; however, dimensional constraints make this challenging. Here, we demonstrate a microscale 3D-printed device capable of minimally-invasive side-viewing OCT image-guided cryobiopsy though uTNE scopes.

Conference Presentation

Citation Download Citation

Radhika K. Poduval, David O. Otuya, Shoumik Lodh, Seth Judson, Darina Postupaka, Abigail L. Gregg, and Guillermo J. Tearney "OCT image guidance for gastrointestinal endoscopic cryobiopsy", Proc. SPIE PC11937, Endoscopic Microscopy XVII, PC119370I (7 March 2022); https://doi.org/10.1117/12.2612714

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