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7 March 2022 Feasibility and safety of tethered capsule endomicroscopy in studying the natural history of Barrett’s esophagus: a multi-center study
Jing Dong, Catriona N. Grant, Barry Vuong, Norman S. Nishioka, Anna Huizi Gao, Matthew Beatty, Grace Baldwin, Aaron Bailargeon, Ara B. Bablouzian, Patricia Grahmann, Nitasha G. M. Bhat, Emily Ryan, Amilcar Barrios, Paola A. Leon Alarcon, Sarah L. Giddings, Tim N. Ford, Émilie Beaulieu-Ouellet, Seyed Hamid Hosseiny, Irene Lerman, Wolfgang Trasischker, Rohith K. Reddy, Kanwarpal Singh, Michalina J. Gora, Daryl Hyun, Lucille H. Quénéhervé, Michael B. Wallace, Wolfsen C. Herbert, Prateek Sharma, Kenneth K. Wang, Cadman L. Leggett, John M. Poneros, Julian A. Abrams, Charles Lightdale, Samantha Leeds, Mireille Rosenberg, Guillermo J. Tearney
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Proceedings Volume PC11937, Endoscopic Microscopy XVII; PC119370N (2022) https://doi.org/10.1117/12.2610595
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Tethered capsule endomicroscopy (TCE) is a recently developed form of in vivo microscopy based on optical coherence tomography (OCT). With TCE, a small tethered pill is swallowed, procuring high resolution microscopic images of the esophageal wall. TCE does not require sedation and is thus a more rapid and convenient procedure comparing to traditional endoscopic examination. Our group and others have successfully conducted OCT-TCE in pilot, single-center studies that demonstrated the potential of this technology for upper GI tract diagnosis. Here, we demonstrate and evaluate the feasibility and safety of a next generation OCT-TCE system and device in patients with Barrett’s esophagus (BE) and report the initial longitudinal analysis of the natural history of BE.
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Jing Dong, Catriona N. Grant, Barry Vuong, Norman S. Nishioka, Anna Huizi Gao, Matthew Beatty, Grace Baldwin, Aaron Bailargeon, Ara B. Bablouzian, Patricia Grahmann, Nitasha G. M. Bhat, Emily Ryan, Amilcar Barrios, Paola A. Leon Alarcon, Sarah L. Giddings, Tim N. Ford, Émilie Beaulieu-Ouellet, Seyed Hamid Hosseiny, Irene Lerman, Wolfgang Trasischker, Rohith K. Reddy, Kanwarpal Singh, Michalina J. Gora, Daryl Hyun, Lucille H. Quénéhervé, Michael B. Wallace, Wolfsen C. Herbert, Prateek Sharma, Kenneth K. Wang, Cadman L. Leggett, John M. Poneros, Julian A. Abrams, Charles Lightdale, Samantha Leeds, Mireille Rosenberg, and Guillermo J. Tearney "Feasibility and safety of tethered capsule endomicroscopy in studying the natural history of Barrett’s esophagus: a multi-center study", Proc. SPIE PC11937, Endoscopic Microscopy XVII, PC119370N (7 March 2022); https://doi.org/10.1117/12.2610595
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KEYWORDS
Esophagus
Endomicroscopy
Endoscopy
Optical coherence tomography
Safety
Biopsy
Imaging systems
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