Spatially offset Raman spectroscopy for non-invasive in vivo monitoring of hydration status

Anna S. Rourke; Laura Masson; Trevor Voss; Blair Hitchcock; Alda Burston; Anita Mahadevan-Jansen

doi:10.1117/12.2609897

7 March 2022 Spatially offset Raman spectroscopy for non-invasive in vivo monitoring of hydration status

Anna S. Rourke, Laura Masson, Trevor Voss, Blair Hitchcock, Alda Burston, Anita Mahadevan-Jansen

Proceedings Volume PC11956, Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables III; PC119560B (2022) https://doi.org/10.1117/12.2609897
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

The development of a real-time, non-invasive method for assessing hydration status is urgently needed in many communities such as the military and high-performance athletes. A probe-based spatially offset Raman spectroscopy system has been developed to accomplish this goal. Raman spectra, including the fingerprint and high wavenumber regions, have been collected from various tissue depths and superficial anatomical locations from collegiate athletes undergoing strength and conditioning regimens. Urine was collected alongside spectroscopy measurements to compare spectral information to urine specific gravity, a clinically relevant hydration metric. Water dynamics shown in spectral features are used to quantify hydration change during exercise regimens.

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Citation Download Citation

Anna S. Rourke, Laura Masson, Trevor Voss, Blair Hitchcock, Alda Burston, and Anita Mahadevan-Jansen "Spatially offset Raman spectroscopy for non-invasive in vivo monitoring of hydration status", Proc. SPIE PC11956, Biophotonics in Exercise Science, Sports Medicine, Health Monitoring Technologies, and Wearables III, PC119560B (7 March 2022); https://doi.org/10.1117/12.2609897

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KEYWORDS

Raman spectroscopy

In vivo imaging

Fiber optics

Macromolecules

Optical fibers

Physiology

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