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7 March 2022 Assessing aggressive prostate cancer in intact prostate with a translational needle photoacoustic sensing probe
Guan Xu, Linyu Ni, Wei-Kuan Lin, Javed Siddiqui, Matthew Allaway, L. Jay Guo, Xueding Wang, Aaron Udager
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Proceedings Volume PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022; PC1196007 (2022) https://doi.org/10.1117/12.2609235
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
This study examined the performance of a clinical translatable needle photoacoustic sensing probe in intact prostates removed through prostatectomy procedures. Compared to the prototype probe in our previous studies, the latest version probe possesses fiber optic hydrophone with a dome-shaped tip that provides better sensitivity and sampling volume. The optical components were integrated into a customized clinical standard steel needle with a side opening and protected by medical grade polyurethane. The needle probe was examined in a setup mimicking a transrectal ultrasound guided transperineal prostate biopsy procedure. Preliminary tests showed promising results in differentiating between benign and aggressive cancer tissues in prostate.
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Guan Xu, Linyu Ni, Wei-Kuan Lin, Javed Siddiqui, Matthew Allaway, L. Jay Guo, Xueding Wang, and Aaron Udager "Assessing aggressive prostate cancer in intact prostate with a translational needle photoacoustic sensing probe", Proc. SPIE PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022, PC1196007 (7 March 2022); https://doi.org/10.1117/12.2609235
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KEYWORDS
Prostate
Photoacoustic spectroscopy
Prostate cancer
Fiber optics
Tissues
Biopsy
Principal component analysis
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