Quantitative elastography of the optic nerve head using confocal acoustic radiation force optical coherence tomography

Fengyi Zhang; Yan Li; Runze Li; Qifa Zhou; Zhongping Chen

doi:10.1117/12.2609251

2 March 2022 Quantitative elastography of the optic nerve head using confocal acoustic radiation force optical coherence tomography

Fengyi Zhang, Yan Li, Runze Li, Qifa Zhou, Zhongping Chen

Author Affiliations +

Proceedings Volume PC11962, Optical Elastography and Tissue Biomechanics VIV; PC119620G (2022) https://doi.org/10.1117/12.2609251
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

The previous researches have demonstrated biomechanical elasticity of optic nerve head is associated with multiple ophthalmic diseases. In this work, we have demonstrated a method to quantify in-vivo elastography of ONH, by using a confocal lamb wave acoustic radiation force optical coherence elastography (ARF-OCE). The ARF-OCE system is based on a phase resolved SD-OCT system combined with an acoustic transducer. Experiments were performed on New Zealand White rabbit eyes in vivo after anesthesia. We have obtained 3D reconstructed OCT images of ONH and the time-resolved elastic map of peripheral retina under various Intraocular pressure.

Conference Presentation

Citation Download Citation

Fengyi Zhang, Yan Li, Runze Li, Qifa Zhou, and Zhongping Chen "Quantitative elastography of the optic nerve head using confocal acoustic radiation force optical coherence tomography", Proc. SPIE PC11962, Optical Elastography and Tissue Biomechanics VIV, PC119620G (2 March 2022); https://doi.org/10.1117/12.2609251

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