Corneal biomechanical parameters of keratoconus patients from cross-meridian air-puff deformation optical coherence tomography and finite element modeling

Judith S. Birkenfeld; Andrea Curatolo; Ashkan Eliasy; Eduardo Martinez-Enriquez; Alejandra Varea; Ana María Gonzalez Ramos; Ahmed Abass; Bernardo Lopes Teixeira; Jesus Merayo-Lloves; Ahmed Elsheikh; Susana Marcos

doi:10.1117/12.2609816

2 March 2022 Corneal biomechanical parameters of keratoconus patients from cross-meridian air-puff deformation optical coherence tomography and finite element modeling

Judith S. Birkenfeld, Andrea Curatolo, Ashkan Eliasy, Eduardo Martinez-Enriquez, Alejandra Varea, Ana María Gonzalez Ramos, Ahmed Abass, Bernardo Lopes Teixeira, Jesus Merayo-Lloves, Ahmed Elsheikh, Susana Marcos

Author Affiliations +

Proceedings Volume PC11962, Optical Elastography and Tissue Biomechanics VIV; PC119620R (2022) https://doi.org/10.1117/12.2609816
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Quantification of the corneas´ biomechanical properties helps to diagnose corneal abnormalities early, which is key in keratoconus (KC) management and treatment. We recently introduced a multi-meridian air-puff ssOCT system capable of acquiring corneal deformation images during air-puff excitation on two meridians. Two healthy and three KC patients were measured with the system. The results were used to quantify deformation asymmetries and as input data for Finite Element (FE) modeling, which was used to estimate corneal biomechanical properties by means of an inverse analysis. Deformation asymmetry parameters and the estimated tangent modulus for healthy and KC corneas are presented and compared.

Conference Presentation

Citation Download Citation

Judith S. Birkenfeld, Andrea Curatolo, Ashkan Eliasy, Eduardo Martinez-Enriquez, Alejandra Varea, Ana María Gonzalez Ramos, Ahmed Abass, Bernardo Lopes Teixeira, Jesus Merayo-Lloves, Ahmed Elsheikh, and Susana Marcos "Corneal biomechanical parameters of keratoconus patients from cross-meridian air-puff deformation optical coherence tomography and finite element modeling", Proc. SPIE PC11962, Optical Elastography and Tissue Biomechanics VIV, PC119620R (2 March 2022); https://doi.org/10.1117/12.2609816

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available