Going deep: Watt W. Webb and my journey in multiphoton imaging

Chris Xu

doi:10.1117/12.2605601

7 March 2022 Going deep: Watt W. Webb and my journey in multiphoton imaging

Chris Xu

Proceedings Volume PC11965, Multiphoton Microscopy in the Biomedical Sciences XXII; PC1196501 (2022) https://doi.org/10.1117/12.2605601
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Multiphoton microscopy, invented by Denk, Strickler and Webb in 1990, has changed how we visualize cells by providing high-resolution, non-invasive imaging capability deep within intact biological tissues. In vivo, cellular resolution fluorescence imaging is now routinely achievable at greater than 1 mm depth in mouse brains. In this talk, I will present research on pushing the depth limit of long wavelength 3-photon microscopy. I will reflect on my journey in multiphoton imaging and the enormous impact Watt Webb has had on me in science and in life.

Conference Presentation

Citation Download Citation

Chris Xu "Going deep: Watt W. Webb and my journey in multiphoton imaging", Proc. SPIE PC11965, Multiphoton Microscopy in the Biomedical Sciences XXII, PC1196501 (7 March 2022); https://doi.org/10.1117/12.2605601

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