Multiscale imaging for early cancer detection

Jennifer K. Barton; Andrew Rocha; Travis Sawyer; Sarah Bohndiek

doi:10.1117/12.2658810

17 March 2023 Multiscale imaging for early cancer detection

Jennifer K. Barton, Andrew Rocha, Travis Sawyer, Sarah Bohndiek

Proceedings Volume PC12363, Multiscale Imaging and Spectroscopy IV; PC1236301 (2023) https://doi.org/10.1117/12.2658810
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

High resolution optical imaging modalities such as optical coherence tomography and multiphoton microscopy have excellent specificity and sensitivity for early detection of cancer, however they may have very limited field of view. This small field of view makes visualizing the entirety of organs time-consuming or impractical. Wide field of view optical modalities such as narrowband or multispectral fluorescence imaging can be combined with high resolution imaging to identify suspicious areas for further investigation. Ovarian and gastric cancer both have poor prognosis unless they are detected early. We have utilized the dual field of view technique for examining the fallopian tubes and stomach, in order to create a viable screening method. Sub-mm to few-mm diameter endoscopes are configured with dual optical modalities, either combined in the same device or with a parent/babyscope design.

Conference Presentation

Citation Download Citation

Jennifer K. Barton, Andrew Rocha, Travis Sawyer, and Sarah Bohndiek "Multiscale imaging for early cancer detection", Proc. SPIE PC12363, Multiscale Imaging and Spectroscopy IV, PC1236301 (17 March 2023); https://doi.org/10.1117/12.2658810

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