Frequency Domain Diffuse Optical Spectroscopy (FD-DOS) can measure tissue optical properties and Diffuse Correlation Spectroscopy (DCS) can measure tissue blood flow. We have combined a custom FD-DOS and a custom DCS system to simultaneously measure oxy and deoxy hemoglobin, blood flow, and muscle metabolism of the sternocleidomastoid during inspiratory threshold loading in healthy volunteers. Additionally, we have developed Monte Carlo based multilayer look up tables for both FD-DOS and DCS that take into account both the skin tone and adipose tissue thickness. In the future, this system may assist in monitoring patients under mechanical ventilation, especially during weaning.
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