Wearable diffuse optical tomography with discrete scalable spring-loaded modules

Alvin S. Agato; Hannah E. Devore; Michelle J. Hedlund; William T. Hamic; Anthony C. O'Sullivan; Calamity F. Svoboda; Adam T. Eggebrecht; Edward J. Richter; Joseph P. Culver

doi:10.1117/12.2650862

17 March 2023 Wearable diffuse optical tomography with discrete scalable spring-loaded modules

Alvin S. Agato, Hannah E. Devore, Michelle J. Hedlund, William T. Hamic, Anthony C. O'Sullivan, Calamity F. Svoboda, Adam T. Eggebrecht, Edward J. Richter, Joseph P. Culver

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Proceedings Volume PC12365, Neural Imaging and Sensing 2023; PC123650B (2023) https://doi.org/10.1117/12.2650862
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Our wearable, modular, high-density diffuse optical tomography system addresses the gap for safe, portable, high-resolution neuroimaging technologies. Miniaturized optoelectronics, improved mechanical design, and Wi-Fi connectivity fit into small modules connected to portable power, allowing free movement. Previous systems have sparse grids, retain mobility-restricting tethers, and/or lack spring-loaded optodes. Our high dynamic range, sensitivity, and SNR at a range of source-detector distances improves resolution compared to sparse arrays. In vivo tests show good benchmark metrics as well as retinotopic mapping. The lightweight system has been tested under different ambulatory conditions. Our wearable system addresses the need for portable, high-resolution, noninvasive neuroimaging modalities.

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Alvin S. Agato, Hannah E. Devore, Michelle J. Hedlund, William T. Hamic, Anthony C. O'Sullivan, Calamity F. Svoboda, Adam T. Eggebrecht, Edward J. Richter, and Joseph P. Culver "Wearable diffuse optical tomography with discrete scalable spring-loaded modules", Proc. SPIE PC12365, Neural Imaging and Sensing 2023, PC123650B (17 March 2023); https://doi.org/10.1117/12.2650862

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KEYWORDS

Diffuse optical tomography

Neuroimaging

Signal to noise ratio

High dynamic range imaging

In vivo imaging

Integrated optics

Magnetic resonance imaging

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