CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12367 > Article
Presentation
9 March 2023 Multimodal imaging with ultraviolet photoacoustic remote sensing and interferometric synthetic aperture microscopy
Matthew T. Martell, Nathaniel J. M. Haven, Brendon S. Restall, Roger J. Zemp
Author Affiliations +
Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC123670V (2023) https://doi.org/10.1117/12.2651039
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
A multimodal approach for margin assessment combines fast, cross-sectional imaging using 1050 nm spectral-domain optical coherence tomography (SD-OCT), offering sensitivity to highly-scattering malignant tissues, with complementary sub-cellular resolution and molecular specificity provided by ultraviolet photoacoustic remote sensing virtual histology. The interferometric synthetic aperture microscopy (ISAM) extension to OCT was implemented to achieve spatially-invariant lateral resolution, reducing the resolution disparity between each modality by avoiding numerical aperture trade-offs. System validation included carbon fiber and TiO2 particle phantom imaging, and ex vivo biological imaging was demonstrated in fresh, thick murine tissues, and benign and malignant human breast samples.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Matthew T. Martell, Nathaniel J. M. Haven, Brendon S. Restall, and Roger J. Zemp "Multimodal imaging with ultraviolet photoacoustic remote sensing and interferometric synthetic aperture microscopy", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC123670V (9 March 2023); https://doi.org/10.1117/12.2651039
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Ultraviolet radiation
Interferometry
Photoacoustic spectroscopy
Remote sensing
Synthetic aperture microscopy
Multimodal imaging
Tissues
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top