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6 March 2023 Photoacoustic biopsy using a translational needle probe
Wei-Kuan Lin, Linyu Ni, Xueding Wang, Jay Guo, Guan Xu
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Proceedings Volume PC12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis; PC1237309 (2023) https://doi.org/10.1117/12.2648655
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
In this study, we developed a prototype interstitial all-optical needle photoacoustic (PA) sensing probe for clinical translation. The performance of the PA needle probe was examined with intact human prostates ex vivo in a simulated transrectal ultrasound (US) guided transperineal prostate biopsy procedure. PA spectrum analysis shows statistical difference between the measurements acquired in benign and cancerous regions (n=49, p<0.05). Multivariate analysis using all quantitative measurements can obtain an accuracy close to 90%.
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Wei-Kuan Lin, Linyu Ni, Xueding Wang, Jay Guo, and Guan Xu "Photoacoustic biopsy using a translational needle probe", Proc. SPIE PC12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis, PC1237309 (6 March 2023); https://doi.org/10.1117/12.2648655
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KEYWORDS
Biopsy
Photoacoustic spectroscopy
Fiber optics
Prostate
Principal component analysis
Prostate cancer
Prototyping
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